
GLP-1在不同组织中具有多种作用和广泛的治疗潜力。
GLP-1 shows numerous actions in different tissues, and a broad therapeutic potential.
GLP-1的主要作用是刺激胰岛素分泌并抑制胰高血糖素分泌,从而有助于控制餐后血糖波动。
The main actions of GLP-1 are to stimulate insulin secretion and to inhibit glucagon secretion,thereby contributing to limit postprandial glucose excursions.
GLP-1 可以增强饱腹感而导致体重减轻,此外,GLP-1还抑制胃肠道运动和分泌,可以充当肠胃素和“回肠制动”机制的一部分。
GLP-1 also causes weight loss by increasing satiety. In addition, GLP-1 also inhibits gastrointestinal motility and secretion,and thus acts as an enterogastrone and part of the "ileal brake" mechanism.